There have been a lot of studies on lineup construction and optimization. Should your best hitter bat second? Should the pitcher bat eighth? None are conclusive, but if you do certain things your team is likely to generate a few more runs.
But one thing is seen as being pretty straightforward, you want the guys with the highest OBP toward the top of the lineup so they get more opportunities.
Here is the Pirates OBP by lineup spot going into Saturday's game:
Obviously what jumps out is that the 7 & 8 spots are significantly higher than 1 & 2. If you follow the Pirates you know why, but suffice it to say this is one of the reasons they've had trouble scoring runs for significant stretches at various times this season.
The silver lining? The numbers at top have gotten better. 1 & 2 were both around .300 a month ago.